Indapamide FAQ

Fit 30 yr old male with hypertension and EXTREME pulse pressure - need specialist?

Hi, i am a fit 30 year old non smoker with a low resting pulse of 40 bpm, with an average pulse of 58 across all BP measurements, but i have been diagnosed with essential hypertension by my GP. I have been home monitoring my BP for a few months now - Prior to medication, my BP was 150/81 (n= 41, over 7 days). Taking Coversyl 10 mg only reduced it to 143/77 (n =116, over 45 days). I then tried Coversyl Plus (5mg/1.25 mg), which had even less of an effect (148/80, n = 42 over 17 days). I have now been on Coversyl 10 mg and 1.5 mg indapamide for 5 days (140/72, n =22), and it is having more of an effect, although it appears to drop my diastolic very low when resting - I've had supine measurements (watching the tour de france!) of 146/58. Hence, i am worried about my pulse pressure - my diastolic is low, but my systolic is still high - my average pulse pressure over all this time is 66, with a max of 101 and a min of only 48). Should i see a cardiologist? Cheers all - some extra notes - I'm not worried about my low resting pulse - I'm proud of it ;) I included it as an indication of my fitness level (yes, i have always exercised regularly). Neither parent suffers from high BP. Re: paramedic - from what i can see in the literature, the vogue now seems to be emphasise MAP or mean arterial pressure [MAP = (sys* 1/3 + dia * 2/3) ]- which provides a better estimate of the total stress your organs are under than either the systolic or diastolic alone. If you use MAP as an indicator, i do have mild hypertension, and i do agree with my GP that in my case (physically fit, non-smoker with no genetic history and only 30 years of age) that is somewhat unusual, and probably deserves treatment. I think i will take your advice and get a referall to a specialist though - I'm a little worried about her seeming lack of expertise in the area.

Currently Ezetimibe with attorvastatin is used to control LDL in particular and lipids in general. In my case, My Lp(a)is 55 while lipid range is normal. Is it necessary to add Ezetimibe to statin for Lp(a) in the drug regimen ? 2. Diruitic like Indapamide 1.5 SR or HCTZ 12.5 is contraindicated in person having high uric acid levels without gouty manifestations and on allopurinol 300 ? 4. What are the pssible options for me who is on amlodipine 10 mg Losartan 100 and Atenolol-100. Doctor wants me to delete Amlodipine because of pedal edema- Mild incompetent sapheno femoral junction. If Amlodipine is deleted, what are other options ? Does combinations of Ramipril 10 + Losartan 100 + Atenolol 100 take care of amlodipine ? I am male 50 hypertensive with obesity 105 kg. Non diabetic non smoker non alcoholic stricy vegitarian. Please guide. 5. Is Nicotinic Acid or Fenofibrate helpful in increasing HDL.? I am a brisk walker but unable to increase my HDL. I shall be obliged to receive your gu

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I have been taking Natrilix 2.5mg ( Indapamide Hemihydrate ) for years to control BP. The GP raised them some years ago to two tablets daily when the BP went up a tad. He even suggested three tablets daily when my BP became unstable during a crisis. But this week, on a repeat prescription, my new GP has stated that one tablet a day is all that is necessary as anything beyond that only raises the diuretic action and has no additional effect on BP. Anyone 'in the know' please comment on this ...... appreciate sensible answers only please!

I am currently using Aspirin, Indapamide, Atenolol, Paroxetene, Tildiem LA, Atorvastatin, Ramipril and Insulin.

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